Peyronie's disease is characterized by the formation of hardened tissue (fibrosis) in the penis that causes pain, curvature, and distortion, usually during erection. The penis is the male organ for reproduction and urination. It is composed of two columns of erectile tissue (the corpora cavernosa); the corpus spongiosum, which contains the tube that carries urine and semen from the body (urethra); and the sheath that surrounds the erectile tissue (tunica albuginea). In Peyronie's disease, dense, fibrous scar tissue (plaque) forms in the tunica albuginea.

Because Peyronie's disease involves deformity of an erect penis and may impair sexual intercourse, doctors have historically classified the condition as a form of impotence, currently referred to as erectile dysfunction (ED).

Incidence and Prevalence

According to a report published in 1995 by the National Institutes of Health, Peyronie's disease occurs in about 1% of men. It is most common between the ages of 45 and 60, but it also occurs in young and elderly men. Prevalence may be higher because of reluctance to seek medical attention for the condition and failure to report in cases with mild symptoms.

Causes and Risk Factors

Signs and Symptoms

Diagnosis

Treatment

Complications

Nutrition

BEFORE AND AFTER PICTURES

Peyronie's Disease