Peyronie's disease is characterized by the formation of hardened tissue (fibrosis) in the penis that causes pain, curvature, and distortion, usually during erection. The penis is the male organ for reproduction and urination. It is composed of two columns of erectile tissue (the corpora cavernosa); the corpus spongiosum, which contains the tube that carries urine and semen from the body (urethra); and the sheath that surrounds the erectile tissue (tunica albuginea). In Peyronie's disease, dense, fibrous scar tissue (plaque) forms in the tunica albuginea.

Because Peyronie's disease involves deformity of an erect penis and may impair sexual intercourse, doctors have historically classified the condition as a form of impotence, currently referred to as erectile dysfunction (ED).

Incidence and Prevalence Causes and Risk Factors Signs and Symptoms Diagnosis Treatment Complications Nutrition BEFORE AND AFTER PICTURES